Home > Riviste > Journal of Neurosurgical Sciences > Fascicoli precedenti > Journal of Neurosurgical Sciences 2016 Settembre;60(3) > Journal of Neurosurgical Sciences 2016 Settembre;60(3):385-91

ULTIMO FASCICOLO
 

ARTICLE TOOLS

Estratti

JOURNAL OF NEUROSURGICAL SCIENCES

Rivista di Neurochirurgia


Indexed/Abstracted in: e-psyche, EMBASE, PubMed/MEDLINE, Neuroscience Citation Index, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,651


eTOC

 

REVIEWS  


Journal of Neurosurgical Sciences 2016 Settembre;60(3):385-91

lingua: Inglese

Role of nitric oxide and mechanisms involved in cerebral injury after subarachnoid hemorrhage: is nitric oxide a possible answer to cerebral vasospasm?

Emanuela CROBEDDU 1, Giulia PILLONI 1, Valentina TARDIVO 1, Marco M. FONTANELLA 2, Pier Paolo PANCIANI 2, Giannantonio SPENA 2, Riccardo FORNARO 1, Roberto ALTIERI 1, Alessandro AGNOLETTI 1, Marco AJELLO 1, Francesco ZENGA 1, Alessandro DUCATI 1, Diego GARBOSSA 1

1 Division of Neurosurgery, Department of Neurological Sciences, University of Turin, Turin, Italy; 2 Department of Neurosurgery, University of Brescia, Brescia, Italy


PDF  


Cerebral vasospasm represents the most critical event that could occur after subarachnoid hemorrhage (SAH). Therapy is only partially effective because cerebral arterial constriction is not fully understood yet. One of the most important biological messenger associated to SAH is nitric oxide (NO), that is considered local regulator of cerebral blood flow. Different nitric oxide synthase (NOS) forms play a role in different biological processes, one of which is to link neuronal activity to blood flow in cerebral cortex. We performed a reassessment of the literature to summarize the role of NO as the main inflammatory pathway activated after SAH to clarify its importance for treatment of vasospasm.

inizio pagina

Publication History

Per citare questo articolo

Corresponding author e-mail

giulia.pilloni@libero.it