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Journal of Neurosurgical Sciences 2002 Marzo;46(1):35-8

lingua: Inglese

Cerebellar ­mature terat­o­ma in adult­hood

Zavanone M. 1, Alimehmeti R. 1, Campanella R. 1, Rampini P. 1, Locatelli M. 1, Egidi M. 1, Righini A. 2, Bauer D. 3

1 Institute of Neurosurgery, Polyclinics of Milan, ­IRCCS, Milan;
2 Department of Neuroradiology, Polyclinics of Milan, ­IRCCS, Milan;
3 Department of Neuropathology, Polyclinics of Milan, ­IRCCS, Milan


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Mature terat­o­ma of the pos­te­ri­or cra­ni­al fos­sa in ­adults is extreme­ly ­rare. We ­report a par­tic­u­lar­ly ­rare ­case of ­medio-lat­er­al cer­e­bel­lar ­mature terat­o­ma ­that ­became symp­to­mat­ic in a mid­dle-­aged man. The CT ­revealed the ­lesion of het­er­o­ge­ne­ous den­sity ­with cal­cifi­ca­tions in the sol­id medi­al por­tion. Only the MRI ­could reli­ably ­define the bor­ders of the cys­tic com­po­nent extend­ing ­into the ­left cer­e­bel­lar ­lobe. Histologically the pres­ence of ful­ly ­matured rep­re­sen­ta­tive tis­sues of the 3 ­germ ­layers ­ensured the diag­no­sis of ­mature terat­o­ma. We sug­gest ­that the ­cyst for­ma­tion ­from pro­gres­sive ­latent hem­or­rhage and/or secre­tion ­from the ­gland ­cells of the ­tumor, may be respon­sible for the clin­i­cal decom­pen­sa­tion ­even in adult­hood.

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