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Rivista di Neurochirurgia

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Periodicità: Bimestrale

ISSN 0390-5616

Online ISSN 1827-1855


Journal of Neurosurgical Sciences 2001 Settembre;45(3):163-70


Central ner­vous ­system ­tumors in Morocco. Retrospective anal­y­sis of 2374 cas­es

Amarti A. 1, Ottmani S. 2, Maher M. 1, Bernoussi Z. 1, Kramlichi A. 3, Saidi A. 1

1 Department of Pathology and Neuropathology, Hôpital des ­spécialités Oto-Neuro-Ophtalmologiques, Rabat, Morocco;
2 Department of Neurosurgery, Hôpital des ­spécialités Oto-Neuro-Ophtalmologiques, Rabat, Morocco;
3 Direction of Epidemiology and Disease Control, Ministry of Health, Rabat, Morocco

Background. No epi­dem­i­olog­i­cal ­data ­about cen­tral ner­vous ­system ­tumors in Morroco ­have ­been pub­lished. The objec­tive of the ­present ­study is to ­assess top­o­graph­ic and dem­o­graph­ic pat­terns of a ­large ­series of his­to­log­i­cal­ly con­firmed ­tumors of central nervous system (CNS), ­skull and ver­te­bral col­umn, exam­ined in the ­main neu­ro­pa­thol­o­gy labor­a­to­ry of the coun­try.
Methods. No. 2363 ­tumors ­have ­been col­lect­ed in the depart­ment of Neu­ro­pa­thol­o­gy in Hôpital des ­spécialités oto-neu­ro-oph­tal­miques, Rabat, ­between 1988 and 1997. Data con­cern­ing age, sex, ­tumor loca­tion and his­to­log­i­cal ­type ­were ­retrieved ­from the labor­a­to­ry ­files. Histological typ­ing was ­based on the World Health horganization (WHO) clas­sifi­ca­tion of cen­tral ner­vous ­system ­tumors and grad­ing on the Kernohan and Mayo Clinic-St. Anne ­systems.
Results. No. 1454 intra­pa­ren­chy­ma­tous and 904 extrap­a­ren­chy­ma­tous ­tumors ­were stud­ied. The top­o­graph­ic repar­ti­tion of ­these ­tumors pre­sent­ed no dif­fer­enc­es ­when com­pared to the lit­er­a­ture ­data. The ­main dif­fer­enc­es ­were not­ed for malig­nant astro­cy­to­mas and gli­o­blas­to­mas ­which ­were ­less fre­quent ­than in Western coun­tries and ­occurred in young­er peo­ple. The ­young age of Morrocan pop­u­la­tion prob­ably ­explains ­these find­ings. Childhood ­tumors repar­ti­tion was sim­i­lar to Western ­series.
Conclusions. These ­results emphaz­ise the ­need for a pop­u­la­tion ­based reg­is­try in ­order to ver­i­fy our find­ings and ­adapt effi­cient ­health inter­ven­tion.

lingua: Inglese


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