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Journal of Neurosurgical Sciences 1998 March;42(1):33-6

lingua: Inglese

­CBF ­change ­with ­aging in moy­a­moya dis­ease

Hirofumi Oyama, Masahiro Niwa, Yoshihisa Kida

Department of Neurosurgery, Komaki City Hospital, Komaki City, Aichi, Japan


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The ­change of cere­bral ­blood ­flow (­CBF) ­with ­aging ­was anal­ized in 9 cas­es of moy­a­moya dis­ease ­whose ­age ­ranged ­from 16 ­years ­old to 58 ­years ­old. ­CBF ­decreased ­more prom­i­nent­ly in ­the var­i­ous ­lobes ­with ­aging ­than con­trol sub­jects ­and ­the decre­ment ­was ­more rap­id in ­the affect­ed ­side ­than in ­the ­non-affect­ed ­side. ­CBF ­was ­thought to ­decrease ­with ­the hemor­rhag­ic ­attack ­and ­the accom­pa­ny­ing neu­ro­log­i­cal dete­ri­ora­tion. However ­the grad­u­al­ly-dete­ri­orat­ing ­brain dam­ag­es ­caused by ­the chron­ic hypo­per­fu­sion ­also ­might be ­engaged in ­this ­CBF decre­ment.

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