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Rivista sulle Malattie dell’Apparato Respiratorio


Official Journal of the Italian Society of Thoracic Endoscopy
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Minerva Pneumologica 2014 Marzo;53(1):43-5

lingua: Inglese

Hepatotoxicity due to montelukast: a case-based review of literature

Sargin G. 1, Coskun A. 2, Yavasoglu I. 3, Yasa M. H. 2

1 Department of Internal Medicine Adnan Menderes University Medical Faculty Aydin, Turkey;
2 Division of Gastroenterology Adnan Menderes University Medical Faculty Aydin, Turkey;
3 Division of Hematology Adnan Menderes University Medical Faculty Aydın, Turkey


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Montelukast is a selective antagonist of cysteinyl leukotriene receptors. Drug-induced hepatotoxicity and abnormal levels of serum aminotransferases may be detected in patients without any clinical symptoms. In literature, several side effects about montelukast have been reported with clinical sings such as jaundice etc. with elevated bilirubin levels. Here, we report 60-year-old female patient who had a medical history about montelukast receiving and elevated serum aminotransferases without any clinical sings.

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