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Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,532
Online ISSN 1827-1715
Pietro FERRARA 1, 2, Francesca IANNIELLO 1, Virginia BIANCHI 3, Fabio QUINTARELLI 2, Michela CAMMERATA 2, Enrica QUATTROCCHI 2, Gloria M. TERRANOVA 2, Giacinto A. MIGGIANO 4, Manuele CASALE 5
1 Institute of Pediatrics, Catholic University Medical School, Rome, Italy; 2 Service of Pediatrics Campus Bio-Medico University, Rome, Italy; 3 Food Sciences and Human Nutrition Unit, Campus Bio-Medico University, Rome, Italy; 4 Service of Clinical Nutrition, Catholic University of Sacred Heart, Rome, Italy; 5 Unit of Otolaryngology, Campus Bio-Medico University, Rome, Italy
BACKGROUND: To demonstrate whether supplementation of vitamin C has a beneficial effect in the prevention of recurrent respiratory tract infections (RTIs) in children. Moreover, we evaluate the main risk factors that predispose to the development of this disease.
METHODS: Sixty children have been enrolled in the study and randomized into two groups: the control group (G1 n = 33) and the group at risk of recurrent RTIs (G2 n = 27). To G2 group was administered every day 100% orange juice with the content of vitamin C 70 mg.
RESULTS: Significant reduction in the incidence rate of RTIs (episodes pre-treatment: 182-6.75 episodes/child, after-treatment: 71-2.62 episodes/child, P <0.05), were observed in G2 group.
CONCLUSIONS: The administration of vitamin C had a beneficial effect in our group of children with recurrent RTIs, reducing the number of infective episodes.