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FASCICOLI E ARTICOLI   I PIÙ LETTI   eTOC

ULTIMO FASCICOLOMINERVA PEDIATRICA

Rivista di Pediatria, Neonatologia, Medicina dell’Adolescenza
e Neuropsichiatria Infantile

Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,532

Periodicità: Bimestrale

ISSN 0026-4946

Online ISSN 1827-1715

 

Minerva Pediatrica 2016 Nov 17

An investigation into respiratory tract viruses in children with acute lower respiratory tract infection or wheezing

Demet DABANIYASTI 1, Fahriye EKSI 1, Özlem KESKIN 2, Mehmet Y. ÖZKARS 2, Tekin KARSLIGIL 1, Iclal BALCI 1

1 Department of Medical Microbiology Gaziantep University, Faculty of Medicine, Gaziantep, Turkey; 2 Pediatric Allergy and Immunology Unit, Gaziantep University, Faculty of Medicine, Gaziantep, Turkey

BACKGROUND: This study aimed to determine the frequencies of respiratory tract viruses in patient (acute lower respiratory tract infection (LRTI) or wheezing) and control (history of asthma without symptoms) groups.
METHODS: Using multiplex­PCR, respiratory tract viruses were investigated in the respiratory tract specimens from patient and control groups followed in the Pediatric Clinic.
RESULTS: The viruses detected in the patient and control groups (p=0.013) were as follows, respectively: rhinoviruses A, B, C (25.6% and 36.7%), influenza virus A (21.1% and 0.0%), parainfluenza virus type 1 (7.8% and 1.7%), parainfluenza virus type 4 (5.6% and 0.0%), adenoviruses A, B, C, D, E (4.4% and 1.7%), parainfluenza virus type 3 (4.4% and 1.7%), coronaviruses 229E and NL63 (4.4% and 1.7%), coronavirus OC43 (3.3% and 0.0%), respiratory syncytial virus A (3.3% and 0.0%), parainfluenza virus type 2 (2.2% and 0.0%), influenza virus B (2.2% and 0.0%), and respiratory syncytial virus B (1.1% and 1.7%). No bocavirus, metapneumovirus or enterovirus was found in any specimen. Statistically significant differences in the detection of influenza virus A (p=0.000), the total detection of parainfluenza viruses (p=0.008) and co­infection (p=0.004) were observed between the patient and control groups.
CONCLUSIONS: The advantage of our study compared with other studies is the inclusion of not only wheezing patients but also children with asthma without symptom. The higher detection of Rhinoviruses both in patient and control groups give rise to thought that these viruses may be responsible for asthma exacerbations and may be related with long duration of virus shedding.

lingua: Inglese


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