Home > Riviste > Minerva Pediatrica > Fascicoli precedenti > Articles online first > Minerva Pediatrica 2015 Sep 11

ULTIMO FASCICOLO
 

ARTICLE TOOLS

Estratti
Per citare questo articolo

MINERVA PEDIATRICA

Rivista di Pediatria, Neonatologia, Medicina dell’Adolescenza
e Neuropsichiatria Infantile


Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,764


eTOC

 

Minerva Pediatrica 2015 Sep 11

Copyright © 2015 EDIZIONI MINERVA MEDICA

lingua: Inglese

Spirometry in children with asthma and/or allergic rhinitis: comparison of FEF25-75% with the standard measures

Eke Gungor H. 1, Sahiner U. M. 1, Altuner Torun Y. 2

1 Kayseri Education and Research Hospital, Department of Pediatric Allergy and Immunology, Erkilet Kayseri, Turkey; 2 Kayseri Education and Research Hospital, Department of Pediatric Hematology, Erkilet Kayseri, Turkey


PDF  


AIM: Forced expiratory flow between 25%and75% of vital capacity (FEF25-75%), a spirometric measure of small airways, may predict the presence of airway responsiveness both in asthmatics and in allergic rhinitics. We aimed to search the correlation between FEF25-75% and standard measures of spirometry (FEV1% and FEV1/FVC) in different clinical conditions, that is in children with asthma, in children with asthma and allergic rhinitis, in children with allergic rhinitis and in healthy children
METHODS: Children with asthma(n=116), asthma plus allergic rhinitis(n=25), allergic rhinitis(n=75) and healthy controls(n=52) were evaluated. Clinical examinations, spirometry and bronchodilation tests were performed.
RESULTS: In asthmatics there was a strong correlation between FEF25-75% and FEV1%(r=0.596, p<0.001); and between FEF25-75% and FEV1/FVC(r=0.740, p<0.001). In AR patients correlation between FEF25-75% and FEV1%(r=0.367, p=0.001); and between FEF25-75% and FEV1/FVC(r=0.534, p<0.001) were less prominent compared to asthmatics but they were still significant and strong. In children with both allergic rhinitis (AR) and asthma correlation between FEF25-75% and FEV1%(r=0.633, p=0.001) and between FEF25-75% and FEV1/FVC(r=0.539, p=0.005) were again significant. Pre-test FEV1% and FEF25-75% in AR patients were lower than that of the control subjects. After the bronchodilation, percentage change in the FEV1 in AR patients were significantly higher then the control subjects(p=0.010). AR patients showed significant increases in FEV1%, (p<0.001), FEF25-75%, (p<0.001) and , (p=0.001) after the bronchodilation test. Within the AR patients only 12/75(16.0%) showed bronchodilation with salbutamol. Among the ones with a FEF25-75% <65% FEV1% was normal in 6/43 (14%) patients in asthmatics and FEV1% was normal in 3/9 (33%) patients in asthma +AR patients.
CONCLUSION: Besides the FEV1% and FEV1/FVC, the FEF25-75% may be a useful and early spirometric parameter to evaluate the children with asthma and or AR.

inizio pagina

Publication History

Per citare questo articolo

Eke Gungor H, Sahiner UM, Altuner Torun Y. Spirometry in children with asthma and/or allergic rhinitis: comparison of FEF25-75% with the standard measures. Minerva Pediatr 2015 Sep 11. 

Corresponding author e-mail

umsahner@yahoo.com