Home > Riviste > Minerva Pediatrica > Fascicoli precedenti > Articles online first > Minerva Pediatrica 2015 Jun 04

ULTIMO FASCICOLO
 

ARTICLE TOOLS

Estratti
Per citare questo articolo

MINERVA PEDIATRICA

Rivista di Pediatria, Neonatologia, Medicina dell’Adolescenza
e Neuropsichiatria Infantile


Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,764


eTOC

 

Minerva Pediatrica 2015 Jun 04

Copyright © 2015 EDIZIONI MINERVA MEDICA

lingua: Inglese

Sleep disordered breathing in a cohort of children with achondroplasia: correlation between clinical and instrumental findings

Zaffanello M. 1, Lo Tartaro P. 1, Piacentini G. 1, Cantalupo G. 2, Gasperi E. 1, Antoniazzi F. 1

1 Pediatric Division, Department of Life and Reproduction Sciences, University of Verona, Verona, Italy; 2 Department of Life and Reproduction Sciences, Child Neuropsychiatry Division, University of Verona, Verona, Italy


PDF  


AIM: The aim of the present study was to show the results of an overnight polysomnography in a cohort of 9 children (7 females and 2 males) with achondroplasia, aged between 1 and 12 years (5.56 ± 4.7 years). All of the children carried the Gly380Arg (G380R) mutation on the FGFR3 gene.
METHODS: All the young patients underwent nocturnal polysomnography without sleep deprivation. Sleep staging was noted according to the guidelines of the American Academy of Sleep Medicine. At the time of registration, the parents answered to a Sleep Control Test questionnaire regarding medical history and diurnal and nocturnal symptoms of their children.
RESULTS: Respiratory sleep disorder was present in 78% of cases, and was generally mild. In 67% of the children there was respiratory effort for more than 30% of the total sleep time. The sample was divided into two age categories: 5 children under the age of 3 years and 4 children over 10 years old. A higher incidence of sleep disorder was found in the first few years of life, where the obstructive pattern predominates. Regarding sleep architecture, we did not find macroscopic alterations of sleep architecture and its phasic manifestations in our paediatric group. However, parents have not been referred daytime sleepiness, attention deficiency, hyperactivity and nocturnal enuresis. Only one had referred recurrent respiratory infections.
CONCLUSION: Polysomnography is a very useful tool in the evaluation of sleep-disordered breathing in children with achondroplasia.

inizio pagina

Publication History

Per citare questo articolo

Zaffanello M, Lo Tartaro P, Piacentini G, Cantalupo G, Gasperi E, Antoniazzi F. Sleep disordered breathing in a cohort of children with achondroplasia: correlation between clinical and instrumental findings. Minerva Pediatr 2015 Jun 04. 

Corresponding author e-mail

marco.zaffanello@univr.it