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Rivista di Pediatria, Neonatologia, Medicina dell’Adolescenza
e Neuropsichiatria Infantile
Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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Minerva Pediatrica 2015 April;67(2):111-6
The use of “2-octyl cyanoacrylate” as skin adhesive in pediatric and congenital cardiac surgery
Vida V. L. 1, Barzon E. 2, Sabiu C. 2, De Franceschi M. 2, Padalino M. A. 1, Stellin G. 1 ✉
1 Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac Thoracic and Vascular Sciences, University of Padua, Padua, Italy;
2 Cardiac Intensive Care Unit, Department of Cardiac Thoracic and Vascular Sciences, University of Padua, Padua, Italy
AIM: The aim of this paper was to evaluate the safety and cost-effectiveness of “2-octyl-cyanoacrylate” as skin adhesive in congenital heart surgery.
METHODS: From April 2010 to December 2011, we collected data from 300 patients who underwent cardiac surgery for congenital heart disease. We divided our population into 3 groups: group-1 (N.=100):“2-octyl-cyanoacrylate” has been used to replace the intra-dermal suture line; group-2 (N.=100):“2-octyl-cyanoacrylate” has been utilized as a barrier (“add-on measure”) in addition to the intra-dermal suture line, group-3 (N.=100) with a standard intra-dermal suture line.
RESULTS: Median age of patients was 1.36 years. One-hundred and thirty-nine patients were younger than 12 months and 56 older than 16 years. There were 11 wound dehiscence (3.6%) (2 in group-1 and 9 in group-3, P=0.001) and 1 superficial wound infection (group-1). Six patients (2%) required surgical wound revision (2 in group-1 and 4 in group-3, P=NS). Wound complication was significantly associated to delayed sternal closure (3/12 patients, 25% versus 13/288 patients, 4.5%) (P=0.04). Median cost (intra-/postoperative) for wound treatment was lower in group-1 and 2 (19±5.5 and 23.9±7.4 € respectively) when compared to Group-3 (26.7±3.2) (P<0.0001).
CONCLUSION: The use of “2-octyl-cyanoacrylate” proved to be safe and effective; the “add-on measure” strategy provided the best cost-effective solution.