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Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,532
Online ISSN 1827-1715
Vida V. L. 1, Barzon E. 2, Sabiu C. 2, De Franceschi M. 2, Padalino M. A. 1, Stellin G. 1
1 Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac Thoracic and Vascular Sciences, University of Padua, Padua, Italy;
2 Cardiac Intensive Care Unit, Department of Cardiac Thoracic and Vascular Sciences, University of Padua, Padua, Italy
AIM: The aim of this paper was to evaluate the safety and cost-effectiveness of “2-octyl-cyanoacrylate” as skin adhesive in congenital heart surgery.
METHODS: From April 2010 to December 2011, we collected data from 300 patients who underwent cardiac surgery for congenital heart disease. We divided our population into 3 groups: group-1 (N.=100):“2-octyl-cyanoacrylate” has been used to replace the intra-dermal suture line; group-2 (N.=100):“2-octyl-cyanoacrylate” has been utilized as a barrier (“add-on measure”) in addition to the intra-dermal suture line, group-3 (N.=100) with a standard intra-dermal suture line.
RESULTS: Median age of patients was 1.36 years. One-hundred and thirty-nine patients were younger than 12 months and 56 older than 16 years. There were 11 wound dehiscence (3.6%) (2 in group-1 and 9 in group-3, P=0.001) and 1 superficial wound infection (group-1). Six patients (2%) required surgical wound revision (2 in group-1 and 4 in group-3, P=NS). Wound complication was significantly associated to delayed sternal closure (3/12 patients, 25% versus 13/288 patients, 4.5%) (P=0.04). Median cost (intra-/postoperative) for wound treatment was lower in group-1 and 2 (19±5.5 and 23.9±7.4 € respectively) when compared to Group-3 (26.7±3.2) (P<0.0001).
CONCLUSION: The use of “2-octyl-cyanoacrylate” proved to be safe and effective; the “add-on measure” strategy provided the best cost-effective solution.