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Rivista di Oftalmologia
Minerva Oftalmologica 2015 June-December;57(2-4):11-5
Thickness of the retinal fibres in young people with myopia measured by optical coherence tomography
Morreale Bubella R., Morreale Bubella D.
Section of Ophthalmology, Department of Experimental Biomedicine and Clinical Neuroscience (BioNeC), University of Palermo, Palermo, Italy
AIM: Our study aimed to study through optical coherence tomography (OCT), in a homogeneous group of subjects with various degrees of myopia, the macular thickness and that of the retinal nerve fiber (RNFL) with the purpose of highlighting the possible presence of a correlation between their impairment and the degree of myopia.
METHODS: Eighty-three students of the Faculty of Medicine and Surgery of the University of Palermo were considered, divided into 4 groups, 3 groups according to the degree of myopia and the last group (control group) including emmetropic subjects. Each subject was submitted to a determination of visual acuity and refractive defect and evaluation of the thickness of the macular fibres and of the RNFL through OCT (Stratus Oct 3000 - Carl Zeiss Meditec inc.).
RESULTS: With a growth in axial length there was a reduction in the average macular thickness in all quadrants of the parafovea with the exception of the superior one. By contrast, in the foveola and fovea there was an increase in thickness with a rise in the refractive defect. The lowest thickness was found in the emmetropic subject.
CONCLUSION: The data found therefore allow us to conclude, in agreement with other studies, that the progressive increase in axial length in myopic subjects involves reshaping of the arrangement of the nerve fibres which needs to be taken into account, especially in subjects with glaucoma that are also very myopic.