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Minerva Medica 2016 Ottobre;107(5):322-7

lingua: Inglese

Role of Prognostic Nutritional Index in patients with gastric cancer: a meta-analysis

Sui H. WANG, Shu T. ZHAI, Hui LIN

Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China


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INTRODUCTION: The aim of this study was to determine the role of Prognostic Nutritional Index in predicting gastric cancer.
EVIDENCE ACQUISITION: Studies were searched in PubMed, EMBASE and ISI Web of Science. The hazard ratios and 95% confidence interval for survival estimate were extracted from the articles and the pooled HR was computed.
EVIDENCE SYNTHESIS: Nine studies with 3203 participants met the inclusion criteria. Low PNI was associated with poor overall survival (pooled HR 1.92, 95% CI: 1.68-2.19).
CONCLUSIONS: Prognostic Nutritional Index was an effective indicator for the prognosis of gastric cancer.

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