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Minerva Endocrinologica 1999 Giugno;24(2):77-82

lingua: Inglese

Physiopathology of the renin-angiotensin system in the ovary

De Nuccio I., Salvati G., Genovesi G., Paolini P., Marcellini L., Schiavello V., Re M.


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The present review confirms the existence of the so called ''ovarian -derived prorenin-angiotensin cascade''. It ialso describes the physiopathology of the system and,cosequently,its role in the genesis of phenomena concerning reproductive function such as ovulation,steroid synthesis and folliculogenesis. Moreover,the ''ovarian-derived prorenin-angiotensin cascade'' appears to play an important role in the aethipotogenesis of diseases such as ovarian tumours,ovarian hyperstimulation syndrome and ectopic pregnancy.

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