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Rivista di Chirurgia
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,877
Minerva Chirurgica 2017 Apr 19
Copyright © 2017 EDIZIONI MINERVA MEDICA
Preservation of duodenal passage as a determinant of short- and long-term quality of life in gastric cancer patients after total gastrectomy
Tomasz OLESIŃSKI ✉, Marek SZPAKOWSKI, Piotr SARAMAK, Andrzej RUTKOWSKI, Krzysztof JEZIORSKI
Department of Oncological Gastroenterology, Maria Sklodowska-Curie Memorial Cancer Center, Warsaw, Poland
BACKGROUND: The aim of this prospective study was to compare subjective and objective quality of life (QoL) of gastric cancer patients after total gastrectomy with and without preservation of the duodenal passage during short- and long-term follow-up.
METHODS: The study included 68 patients, among them 37 (54%) persons subjected to total gastrectomy with Roux-Y reconstruction (R-Y group) and 31 (46%) individuals in whom gastrectomy was followed by formation of Henley-Longmire loop (H-L group). Subjective and objective QoL was determined 1 and 10 years post-surgery. During each visit, subjective QoL was determined with EORTC QLQ-C30 questionnaire, along with markers of nutritional status and self-reported incidence of symptoms specific to post-gastrectomy syndrome.
RESULTS: The two groups did not differ significantly in terms of their subjective QoL and markers of nutritional status at 1 and 10 years post-surgery, and none of these parameters underwent significant changes between the first and second evaluation. Patients from R-Y group reported subjective weight loss significantly more often during both visits, and individuals from H-L group significantly more often complained on postprandial diarrhea during long-term follow-up. Moreover, both groups showed an increase in the incidence of postprandial vomiting between the first and second evaluation.
CONCLUSIONS: QoL of gastric cancer patients subjected to total gastrectomy stabilizes at relatively high level within a year from the surgery. Preservation of the duodenal passage does not exert a beneficial effect on both objective and subjective QoL after total gastrectomy.
KEY WORDS: Dumping syndrome - Post-gastrectomy syndrome - Roux-Y reconstruction - Henley-Longmire loop