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Minerva Chirurgica 2015 February;70(1):23-31

lingua: Inglese

Evaluation of the effectiveness of a hyperoxidized oil-based medication in the treatment of skin lesions: observational study

Cassino R. 1, Ippolito A. M. 1, Cuffaro P. 1, Corsi A. 2, Forma O. 3

1 Vulnera - Italian Vulnological Center, Turin, Italy;
2 Santa Maria Nuova Hospital, Florence, Italy;
3 San Raffaele Hospital, Milan, Italy


AIM: Aim of the study was to demonstrate the effectiveness, in the management of recalcitrant wounds, of a hyperoxidized oil-based gel with film-forming and protective functions.
METHODS: The study involved 50 patients with recalcitrant not infected and/or necrotic chronic ulcers. All patients had 0.7 minimum ABPI value; terminal and/or cancer and/or under immunosuppressive therapy patients were excluded. The dressing consisted in a uniform gel layer applied on the lesion, after cleansing with a 0.05% sodium hypochlorite chloroxidating solution. The dressing was changed every 48 hours (or every 24 hours, in case of hyperexuding wound). The effectiveness was assessed by the evaluation of the WBP score changes and area reduction (via the Visitrak™ Digital System) after an observation period of 4 weeks.
RESULTS: All patients achieved area improvement; WBP score improved in more than 90% of the B score patients; pain reduction was reported by all patients: more than 55% of the total number of patients limited the use of analgesic drugs and in 6 cases (12%) they discontinued the antalgic therapy.
CONCLUSION: The dressing showed an actual effectiveness, promoting granulation and accelerating epithelialization; no patient suffered from allergy/intolerance and all of them reported a decrease in pain, until complete relief.

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