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Rivista di Biologia Molecolare e Biotecnologie

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Minerva Biotecnologica 2009 September;21(3):173-86

lingua: Inglese

Biomimetic ceramics in implant dentistry

Padial-Molina M. 1, Galindo-Moreno P. 2, Avila-Ortiz G. 1

1 Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA
2 Oral Surgery and Implant Dentistry Department, School of Dentistry, University of Granada, Granada, Spain


Surface modification of biomedical devices for dental and orthopedic use has been investigated to achieve optimal cell response and predictable clinical outcomes. Dental implant properties can be modified to enhance peri-implant wound healing using biomimetic methods. Several biomimetic agents have been proposed to enhance implant surfaces, including ions, bioactive proteins, and bioceramics. Bioceramics present high biocompatibility and are associated with high long-term implant survival rates. A wide variety of bioceramic materials have been developed. They differ in their final chemical composition, crystalline structure, and porosity. Calcium phosphate-based ceramics are the most widely used bioceramics. Remarkable clinical outcomes have been obtained using calcium phosphate-coated implants. Other materials such as silicates and wollastonite have been successfully used as well. This review is aimed at providing an overview of the use of bioceramics to enhance peri-implant wound healing and the rationale behind the use of these promising materials in implant dentistry.

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