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Rivista di Biologia Molecolare e Biotecnologie

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Minerva Biotecnologica 2006 December;18(4):181-4


lingua: Inglese

Anti-bacterial and wound repair potentials of a novel microbial fermentation product

Chui C. H. 1, 2, Gambari R. 3, L.Kok S. H. 2, Lau F. Y. 1, Wong R. S. M. 1, Cheng G. Y. M. 1, Ho K. P. 2, Cheung F. 2, Chan S. S. W. 2, Cheng C. H. 2, Chan A. S. C. 2, Tang J. C. O. 2

1 Department of Medicine and Therapeutics Prince of Wales Hospital The Chinese University of Hong Kong, Hong Kong, P.R China 2 Drug Research and Development Centre B Central Laboratory of the Institute of Molecular Technology for Drug Discovery and Synthesis and State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Shenzhen, China Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic University; Hong Kong, P.R.China 3 ER-GenTech, Department of Biochemistry and Molecular Biology University of Ferrara, Ferrara, Italy


Bacterial infection is an important aspect in skin diseases in animals, including cats and dogs. This could be arise from skin lesion with poor subsequent attention and treatment. Use of antibiotic could enhance the antibiotic resistance problem of the society. Here we have demonstrated that a microbial fermentation product produced by beneficial bacteria could show in vitro growth inhibitory activity on Pseudomonas aeruginosa and Staphylococcus aureus. In vivo consented clinical trial on animals including cat and dog further demonstrated that this microbial fermentation product could induce recovery of wound with bacterial infection as well as clot formation and hair growth. We believe that this novel microbial fermentation product could be used as a therapeutic supplement for wound healing treatment.

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