Home > Riviste > Minerva Biotecnologica > Fascicoli precedenti > Minerva Biotecnologica 2006 June;18(2) > Minerva Biotecnologica 2006 June;18(2):121-7

ULTIMO FASCICOLO
 

ARTICLE TOOLS

Estratti

MINERVA BIOTECNOLOGICA

Rivista di Biologia Molecolare e Biotecnologie


Indexed/Abstracted in: EMBASE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,246


eTOC

 

REVIEWS  TISSUE ENGINEERING


Minerva Biotecnologica 2006 June;18(2):121-7

Copyright © 2006 EDIZIONI MINERVA MEDICA

lingua: Inglese

Stem cells in intervertebral disc tissue engineering

Risbud M. V.

Graduate Program in Tissue Engineering and Regenerative Medicine Department of Orthopaedic Surgery Thomas Jefferson University, Philadelphia, PA, USA


FULL TEXT  


Damaged or diseased intervertebral disc major cause morbidity and frequently leads to a significant reduction in the quality of life. Current tissue-engineering strategies for the regeneration of disc are mainly based on the restoration of pathologically altered tissue structure based on the transplantation of autologous tissue-derive cells or mesenchymal stem cells (MSC) along with supportive scaffolds and biomolecules. However, extensive capacity to proliferate in culture and plasticity of MSC give them an edge over differentiated tissue-derived disc cells. Increased understanding of the molecular mechanism directing lineage specification and morphogenesis of these cells into disc cell phenotype will provide a rational approach for the regeneration of disc.

inizio pagina

Publication History

Per citare questo articolo

Corresponding author e-mail