Home > Riviste > Minerva Biotecnologica > Fascicoli precedenti > Minerva Biotecnologica 2006 March;18(1) > Minerva Biotecnologica 2006 March;18(1):17-22

ULTIMO FASCICOLO
 

ARTICLE TOOLS

Estratti

MINERVA BIOTECNOLOGICA

Rivista di Biologia Molecolare e Biotecnologie


Indexed/Abstracted in: EMBASE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,246


eTOC

 

ORIGINAL ARTICLES  NEW TRENDS IN BIOENCAPSULATION - Part 2


Minerva Biotecnologica 2006 March;18(1):17-22

lingua: Inglese

Hydroxyapatite-alginate structure as living cells supporting system

Krylova E. A. 1, Ivanov A. A. 1, Krylov S. E. 1, Plashchina I. G. 1, Grigorjan S. 2, Goldstein D. V. 3, Pulin A. A. 3, Fatkhudinov T. H. 3

1 N. N. Emanuel Institute of Biochemical Physics RAS, Moscow, Russia
2 Central Scientific Research Institute of Stomatology Moscow, Russia
3 ReMeTex Co., Moscow, Russia


FULL TEXT  


The fabrication of biominerals, such as bone, involves the construction of preorganized organic frameworks that are used as polymer matrix for the formation of nanoscale inorganic crystals. Biomineralized structures can be further assembled by cellular processing in higher-order configurations. Biomineralization of hydroxyapatite calcium (HA) in alginate (ALG) matrix can provide useful archetypes for homogenous chondroblasts from hyaline cartilaginous tissue. The aim of this work was to study the influence of high- and low molecular carbohydrates on the HA crystallization, structures and stability of HA-ALG beads in MEM-serum solutions by FTIR, SEM, and XRD methods. The way of cultivating with the use of stable HA-ALG beads allows get a large amount of proliferating cells, saving their phenotype and synthesizing extracellular matrix.

inizio pagina

Publication History

Per citare questo articolo

Corresponding author e-mail