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Rivista di Anestesia, Rianimazione, Terapia Antalgica e Terapia Intensiva

Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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Minerva Anestesiologica 2016 Nov 23

lingua: Inglese

Comparison of terminal extubation and terminal weaning as mechanical ventilation withdrawal in ICU patients

Damien THELLIER 1, Pierre Y. DELANNOY 1, Olivier ROBINEAU 2, Agnès MEYBECK 1, Nicolas BOUSSEKEY 1, Arnaud CHICHE 1, Olivier LEROY 1, Hugues GEORGES 1

1 Intensive Care Unit, Hôpital Chatiliez, Tourcoing Cedex, France; 2 Infectious Diseases Unit, Hôpital Chatiliez, Tourcoing Cedex, France


BACKGROUND: Terminal extubation (TE) is applied in some intensive care unit (ICU) patients when a decision of withdrawal of mechanical ventilation is decided. Other units prefer terminal weaning (TW) with no removal of the endotracheal tube. We report our experience with these two procedures.
METHODS: We conducted a retrospective study analyzing patients deceased in our ICU after a decision of life sustained therapy (LST) during the year 2013. TE was proposed to family members for patients presenting with two medical conditions: lack of vasoactive drugs (VAD) and SaO2 > 95% with a FIO2 < 50%. TW, defined by the reduction of oxygenation and/or the discontinuation of VAD, was proposed for patients receiving a FIO2 ≥ 50% and/or VAD. The two procedures were performed after obtaining a Cambridge score-5 with sedatives.
RESULTS: Sixty eight patients died after withdrawal of LST. TE was performed for 22 patients and TW for 46. There was no difference in mean age, mean length of ICU stay, cause of ICU admission and dose of sedatives used during withdrawal procedure between the two groups. All family members approved the decision of TE. In this group, family members of each patient were present in ICU room at time of death, while they were present at this moment for 32 (69.5%) patients with TW.
CONCLUSIONS: In our unit, TE is a practice largely approved by family members. This procedure does not require higher doses of sedatives and allows the nearest relatives to be present at time of death.

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