Home > Riviste > Minerva Anestesiologica > Fascicoli precedenti > Minerva Anestesiologica 2012 April;78(4) > Minerva Anestesiologica 2012 April;78(4):473-82

ULTIMO FASCICOLO
 

ARTICLE TOOLS

Estratti

MINERVA ANESTESIOLOGICA

Rivista di Anestesia, Rianimazione, Terapia Antalgica e Terapia Intensiva


Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 2,623


eTOC

 

REVIEWS  FREEfree


Minerva Anestesiologica 2012 April;78(4):473-82

Copyright © 2012 EDIZIONI MINERVA MEDICA

lingua: Inglese

Myths and facts in neuromuscular pharmacology. New developments in reversing neuromuscular blockade

Fink H. 1, Hollmann M. W. 2

1 Klinik für Anaesthesiologie, Klinikum rechts der Isar der Technischen Universität München, München, Germany; 2 Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands


FULL TEXT  


Pharmacologic reversal of neuromuscular blockade is a topic not very well acknowledged and controversially discussed. Reasons for this are numerous and include missing perception of the potential complications of residual neuromuscular paralysis including an increased morbidity and mortality, as well as low efficacy and numerous unwanted side effects of the available antagonists. Duration of action of muscle relaxants cannot be pharmacologically predicted. Objective neuromuscular monitoring is the only way to detect residual paralysis. This review article would like to discuss in its first part some of the myths which revolve around the use of muscle relaxants, then highlight the problems regarding the use of acetylcholine esterase inhibitors and, in the third part, discuss the steroidal muscle relaxant encapsulator sugammadex.

inizio pagina

Publication History

Per citare questo articolo

Corresponding author e-mail

h.fink@lrz.tum.de