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Rivista di Anestesia, Rianimazione, Terapia Antalgica e Terapia Intensiva

Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 2,036

Periodicità: Mensile

ISSN 0375-9393

Online ISSN 1827-1596


Minerva Anestesiologica 2010 Novembre;76(11):945-9


Limitations of volumetric indices obtained by trans-thoracic thermodilution

Bigatello L. M. 1, Kistler E. B. 2, Noto A. 3

1 Anesthesiology Service, VA Boston Healthcare System, Harvard Medical School, Boston, MA, USA;
2 Department of Anesthesia, University of California at San Diego, San Diego, CA, USA;
3 Department of Cardiothoracic and Vascular Anesthesia, University of Messina, Policlinico G. Martino, Messina, Italy

Transthoracic thermodilution (TTT) measures cardiac output without the need for right heart catheterization. In addition, two volumetric hemodynamic indices have been derived from the mathematical analysis of the TTT curve: the global end diastolic volume (a quantitative measure of cardiac preload) and the extravascular lung water volume (a quantitative measure of pulmonary edema). Despite the undeniable appeal of these two novel parameters, uncertainty exists regarding both the validity of their mathematical derivation and their physiological significance. This concise review attempts to discuss such concerns.

lingua: Inglese


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