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Rivista di Angiologia
Official Journal of the , the International Union of Phlebology and the
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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International Angiology 2010 June;29(3):244-8
Duration of aortic cross-clamping during elective open abdominal aortic aneurysm repair operations and postoperative cardiac/renal function
Georgakis P. 1, Paraskevas K. I. 2, Bessias N. 2, Mikha-ilidis D. P. 3, Andrikopoulos V. 2, Katsouli-Liapis I. 1 ✉
1 Department of Anesthesiology, Red Cross Hospital, Athens, Greece;
2 Department of Vascular Surgery, Red Cross Hospital, Athens, Greece
AIM: To determine the effect of the duration of aortic cross-clamping during elective infrarenal abdominal aortic aneurysm (AAA) repair operations on postoperative cardiac and renal function.
METHODS: Fifty patients scheduled for open infrarenal AAA repair underwent pre- and postoperative evaluation of serum creatinine and troponin levels. The patients were divided into 2 groups according to the duration of aortic cross-clamping (Group A: <50 min; Group B: >50 min).
RESULTS: A prolonged (>50 min) duration of aortic cross-clamping was associated with an increase in post-operative serum troponin (P<0.001) and serum creatinine values (P<0.001). A prolonged duration of aortic cross-clamping was the only independent predictor of postoperative renal (r=0.534; P<0.001) and cardiac dysfunction (r=0.578; P<0.001).
CONCLUSION: Elective open infrarenal AAA repair procedures may be associated with mild/moderate cardiac and/or renal dysfunction, especially when aortic cross-clamping time is prolonged. Measuring serum troponin and creatinine levels before and after such operations may reveal an often clinically-silent post-operative cardiac and/or renal dysfunction.