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INTERNATIONAL ANGIOLOGY

Rivista di Angiologia


Official Journal of the International Union of Angiology, the International Union of Phlebology and the Central European Vascular Forum
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International Angiology 2004 June;23(2):134-8

Copyright © 2004 EDIZIONI MINERVA MEDICA

lingua: Inglese

Prevalence of lower limb occlusive vascular disease in outclinic diabetic patients

Andrade J. L., Schlaad S. W., Koury Junior A., Van Bellen B.

Division of Vascular Surgery, Beneficência Portuguesa Hospital, São Paulo, Brazil


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Aim. The aim of this study was to deter­mine the prev­a­lence and risk fac­tors for periph­er­al occlu­sive vas­cu­lar dis­ease (POVD) in sub­jects with dia­betes mel­lit­us (DM) in Bra­zil.
Meth­ods. We eval­u­at­ed 236 dia­bet­ic indi­vid­u­als, in spon­ta­ne­ous ­demand, rep­re­sent­ing 471 legs. POVD was ­assessed by the ankle bra­chi­al index (ABI).
­Results. The mean age was 62.1 years (range 22-89 years), 52% were male, 93.2% type II DM and the mean time to diag­no­sis was 7.9 years (range 0-37 years). Sixty per­cent were hyper­ten­sives. In 61% at least one pulse was dimin­ished or ­absent. The prev­a­lence of ische­mia was 18% (ABI<0.9) while 22% had an ABI com­pat­ible with high grade arte­ri­al cal­cifi­ca­tion (ABI>1.3). Over­all less than 1/3 of the cases had the vas­cu­lar exam that could be con­sid­ered nor­mal. The ABI was lower in sub­jects with pulse def­i­cit (p<0.001), and a nor­mal pulse had a neg­a­tive pre­dic­tive value for ische­mia of more than 90%. Sub­jects with nor­mal puls­es were young­er and had a ­decreased dia­betes dura­tion (p<0.001 and p<0.05, respec­tive­ly). An ­increase in the dura­tion of the dia­betes was asso­ciat­ed with a pro­gres­sive ­decrease in the ABI (p<0.01). ­Female gen­der and hyper­ten­sion were asso­ciat­ed with a ­reduced ABI (p<0.01 and p<0.05, respec­tive­ly).
Con­clu­sion. There is a high prev­a­lence of POVD in dia­bet­ic indi­vid­u­als. The dis­ease is asso­ciat­ed with hyper­ten­sion and ­female gen­der and gets worse with increas­ing dura­tion of the dia­betes.

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