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Rivista di Angiologia

Official Journal of the International Union of Angiology, the International Union of Phlebology and the Central European Vascular Forum
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899

Periodicità: Bimestrale

ISSN 0392-9590

Online ISSN 1827-1839


International Angiology 1999 Giugno;18(2):145-8


Fluorescence micro­lym­phog­ra­phy of the upper extrem­ities. Evaluation with a new com­put­er pro­gramme

Lauchli S., Haldimann L. *, Leu A. J., Franzeck U. K.

From the Division of Vascular Medicine (Angiology), Department of Medicine, University Hospital, Zürich,
* Federal Institute of Technology (ETH), Zürich, Switzerland

Background. To eval­u­ate the ­initial lym­phat­ics of the super­fi­cial skin in ­healthy vol­un­teers using flu­o­res­cence micro­lym­phog­ra­phy and to estab­lish con­trols val­ues for com­par­i­son with lym­phed­e­ma ­patients.
Methods. Fluorescence micro­lym­phog­ra­phy was per­formed on the hand dor­sum, on the lower and the upper arm in 12 ­healthy sub­jects (58.7±8.0 years). At each of these sites 10 µl FITC-dex­tran was inject­ed sub­epi­der­mal­ly using a steel can­nu­la. The stud­ies were record­ed on video tape using a flu­o­res­cence micro­scope and a CCD video cam­e­ra. Final mag­nifi­ca­tion was 24 and 62. The max­i­mum ­spread of the flu­o­res­cent con­trast medi­um was meas­ured 10 min­utes after injec­tion. The area of the vis­u­al­ized lymph cap­il­lar­ies was deter­mined using a com­put­er pro­gramme.
Setting. University Hospital, Department of Medicine, Division of Vascular Medicine (Angiology).
Results. The mean area of the vis­u­al­ised lymph cap­il­lary net­work 95.3±41.3 mm2 (42-174 mm) at the upper and 89.4±45.5 mm2 (44-171 mm). The max­i­mum ­spread was 4.8±3.5 mm (1.9-13.6 mm) and 4.4±3.7 mm, respec­tive­ly. The mean diam­e­ter of the lymph cap­il­lar­ies was 84.1±19.9 µm and 75.5±14.8 µm, respec­tive­ly.
Conclusions. The exten­sion of the lymph cap­il­lary net­work at the upper and lower arm are com­par­able to those at the lower extrem­ities. Considering the two-dimen­sion­al ­nature and the irreg­u­lar shape of the net­work the area meas­ure­ment seems to be more appropri-ate than the max­i­mum ­spread in one direc­tion.

lingua: Inglese


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