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Official Journal of the , the International Union of Phlebology and the
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,899
Online ISSN 1827-1839
Lauchli S., Haldimann L. *, Leu A. J., Franzeck U. K.
From the Division of Vascular Medicine (Angiology), Department of Medicine, University Hospital, Zürich,
* Federal Institute of Technology (ETH), Zürich, Switzerland
Background. To evaluate the initial lymphatics of the superficial skin in healthy volunteers using fluorescence microlymphography and to establish controls values for comparison with lymphedema patients.
Methods. Fluorescence microlymphography was performed on the hand dorsum, on the lower and the upper arm in 12 healthy subjects (58.7±8.0 years). At each of these sites 10 µl FITC-dextran was injected subepidermally using a steel cannula. The studies were recorded on video tape using a fluorescence microscope and a CCD video camera. Final magnification was 24 and 62. The maximum spread of the fluorescent contrast medium was measured 10 minutes after injection. The area of the visualized lymph capillaries was determined using a computer programme.
Setting. University Hospital, Department of Medicine, Division of Vascular Medicine (Angiology).
Results. The mean area of the visualised lymph capillary network 95.3±41.3 mm2 (42-174 mm) at the upper and 89.4±45.5 mm2 (44-171 mm). The maximum spread was 4.8±3.5 mm (1.9-13.6 mm) and 4.4±3.7 mm, respectively. The mean diameter of the lymph capillaries was 84.1±19.9 µm and 75.5±14.8 µm, respectively.
Conclusions. The extension of the lymph capillary network at the upper and lower arm are comparable to those at the lower extremities. Considering the two-dimensional nature and the irregular shape of the network the area measurement seems to be more appropri-ate than the maximum spread in one direction.