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Rivista di Angiologia
Official Journal of the , the International Union of Phlebology and the
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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International Angiology 1998 June;17(2):93-6
Prevention of deep vein thrombosis in knee arthroplasty. Preliminary results from a randomized controlled study of low molecular weight heparin vs foot pump compression
Norgren L. *, Toksvig-Larsen S., Magyar G., Lindstrand A., Albrechtsson U.
From the Departments of Orthopedic Surgery and Diagnostic Radiology and Section of Vascular Surgery, Department of Surgery * - Lund University, Sweden
Background. We evaluated in a randomized controlled study the possibility to use foot pump mechanical compression compared to routine LMWH as prophylaxis against deep vein thrombosis during knee arthroplasty.
Methods. Forty patients were included in this preliminary report. Eleven patients withdrew, usually during the early phase of the study.
Results. Among the 29 patients completing a venography, 27% in the compression group and none in the LMWH group had a DVT. This difference was statistically significant (p<0.05). One further patient in the compression group died from pulmonary embolism 17 days postoperatively.
Conclusions. With the present study protocol, mechanical foot pump compression failed to be as efficient as LMWH prophylaxis.