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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2016 January-February;175(1-2):40-7

lingua: Italiano

Iperenzimemia pancreatica benigna o Sindrome di Gullo: incidenza in una popolazione afferente a un dipartimento di emergenza

Letizia M. MURABITO, Fausto FAMA’, Maria A. GIOFFRE’ FLORIO

Unità Operativa Complessa di Medicina e Chirurgia d’Accettazione e d’Urgenza con Osservazione Breve, Azienda Ospedaliera Universitaria Policlinico “G. Martino” di Messina, Messina, Italia


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BACKGROUND: The objective of the study was to assess in patients admitted to Emergency Department University Hospital of Messina, the impact of Gullo’s Syndrome in our population to identify subjects with the syndrome.
METHODS: We analyzed all patients arriving to the Emergency Department, with abnormally high values of serum pancreatic enzymes. Descriptive analysis of the study-subjects hospitalized for a “short” (24-48h) observational evaluation and, after a careful past medical history, repeated determinations of serum enzymes, diagnostic tests, and instrumental monitoring at short, medium and long-term.
RESULTS: Results showed that 36.8% of 389 the study subjects demonstrated a benign pancreatic hyperenzymemia, with prevalence of 0.09% per 100,000 in our sample.
CONCLUSIONS: In this study, highlight the frequency in the population of patients with abnormal levels of pancreatic enzymes. We, also, underline the importance of the serum enzymatic activity evaluation to detect this syndrome, and the role of follow-up to confirm the diagnosis. Extending the knowledge about this syndrome to the whole national territory through the establishment of guidelines, preferably addressed to general practitioners, would allow a correct diagnostic-therapeutic management.

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