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FASCICOLI E ARTICOLI   I PIÙ LETTI

ULTIMO FASCICOLOGAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE

Rivista di Medicina Interna e Farmacologia

Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index

Periodicità: Mensile

ISSN 0393-3660

Online ISSN 1827-1812

 

Gazzetta Medica Italiana Archivio per le Scienze Mediche 2014 Dicembre;173(12):593-600

 ARTICOLI ORIGINALI

Effects of ACE expression and I/D polymorphism on alpine skiing performance

Polat M. 1, Çoksevim B. 2, Taheri S. 3, Dündar M. 3

1 Erciyes University School of Physical Education and Sport, Kayseri, Turkey;
2 Department of Physiology, Erciyes University Faculty of Medicine, Kayseri, Turkey;
3 Department of Medical Genetics, Erciyes University Faculty of Medicine, Kayseri, Turkey

AIM: The aim of this study was evaluate the effects of ACE expression results and I/D polymorphism on performance of elite alpine skiers.
METHODS: A total of 91 volunteer that participated to the study were divided into 4 different groups according to their performance in alpine skiing as the Elite National Group, National Group, Regional Group, and Control Group. Using PCR methods on the blood samples obtained from the volunteers, the ACE I/D polymorphism results as well as the expression results for this gene were obtained.
RESULTS: ACE D/D genotype was found significantly higher in the Elite National Group and the National Group (P<0.05). In addition, expression results of ACE gene were significantly lower in the all skier groups than Control Group (P<0.012).
CONCLUSION: The results obtained within the context of our study show that the presence of the D/D genotype is associated with alpine skiing performance. In addition, the lower levels of ACE gene expression in comparison to the control groups suggest that the activation of this gene may have significant effects on alpine skiing performance.

lingua: Inglese


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