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Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1642
Giovanni CASELLA 1, Bianca M. BORDO 2, Renzo SCHALLING 3, Vincenzo VILLANACCI 4, Marianna SALEMME 4, Camillo DI BELLA 5, Vittorio BALDINI 6, Gabrio BASSOTTI 7
1 Gastroenterology and Hepatology Unit, Medical Department, Desio Hospital, Desio, Monza e Brianza, Italy; 2 Neurology Department, Desio Hospital, Desio, Monza e Brianza, Italy; 3 Gastrointestinal Endoscopy Unit, Vimercate Hospital, Vimercate, Monza e Brianza, Italy; 4 Institute of Pathology, “Spedali Civili” Brescia, Brescia, Italy; 5 Pathology Department, Desio Hospital, Desio, Monza e Brianza, Italy; 6 Medical Department, Desio Hospital, Desio, Monza e Brianza, Italy; 7 Gastro‑Intestinal and Hepatology Section, Department of Medicine, University of Perugia Medical School, Perugia, Italy
Celiac disease (CD) determines neurologic manifestations in 10% of all CD patients. We describe the most common clinical manifestations as cerebellar ataxia, gluten encephalopathy, multiple sclerosis, peripheral neuropathies, sensorineural hearing loss, epilepsy, headache, depression, cognitive deficiencies and other less described clinical conditions. Our aim is to perform, as more as possible, a review about the most recent update on the topics in international literature. It is important to consider clinical neurological manifestations in celiac patients and to research these conditions also in the follow-up because they may start also one year after the start of gluten free diet (GFD) as peripheral neuropathy. The association with autism is analysed and possible new association with non-celiac gluten sensitivity (NCGS) are considered.