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MINERVA GASTROENTEROLOGICA E DIETOLOGICA
Rivista di Gastroenterologia, Nutrizione e Dietetica
Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
Minerva Gastroenterologica e Dietologica 2016 March;62(1):11-8
Multidetector computed tomography angiography in the management of transarterial embolization of primary and secondary liver malignancy
Nikoloz ONASHVILI 1, 2, Malkhaz MIZANDARI 1, Tamta AZRUMELASHVILI 1, Ana INGOROKVA 3, Giorgi UBIRIA 1 ✉
1 Department of Radiology, Tbilisi State Medical University, Tbilisi, Georgia; 2 “Aversi Clinic” ltd, Tbilisi, Georgia; 3 High Technology Medical Center, Tbilisi, Georgia
BACKGROUND: Endovascular management is the mainstay of therapy for most patients with primary and secondary liver tumors. Radiologist should understand the anatomy of the hepatic vasculature and tumor feeding vessels to ensure successful conduction of the embolization procedure. The aim of this study was to evaluate the accuracy of multidetector computed tomographic angiography (MDCTA) for the evaluation of hepatic arterial anatomy and tumor feeding vessels prior to embolization procedure.
METHODS: This study included 42 patients. They were 30 with hepatocellular carcinoma, 6 with colorectal cancer metastases, 3 with intrahepatic cholangiocellular carcinoma, 2 with giant focal nodular hyperplasia and 1 with gallbladder tumor. The findings of MDCTA were compared with the DSA findings, which served as the standard of reference. Sensitivity and specificity of the MDCTA were calculated.
RESULTS: MDCTA showed 100% coincidence with the DSA and 100% accuracy in the evaluation of gross hepatic arterial anatomy and its variations. 61 out of the 64 feeders were correctly identified with the MDCTA. False positives and false negatives were 3 each. Accordingly sensitivity and specificity were 95.31%, 97.95% respectively.
CONCLUSIONS: MDCT angiography permits accurate assessment of the hepatic vascular anatomy. Although some pathways of tumor irrigation may not be well visible on the computed tomography. These require detailed reevaluation of suspected tumor feeders during embolization procedure.