Home > Riviste > Giornale Italiano di Dermatologia e Venereologia > Fascicoli precedenti > Articles online first > Giornale Italiano di Dermatologia e Venereologia 2017 Mar 14





Rivista di Dermatologia e Malattie Sessualmente Trasmesse

Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,311



Giornale Italiano di Dermatologia e Venereologia 2017 Mar 14

DOI: 10.23736/S0392-0488.17.05466-9


lingua: Inglese

Contact sensitization of children referred to the Dermatology Department of the University Federico II of Naples, Italy: a two-decade years history

Serena LEMBO 1, Claudio LEMBO 2, Cataldo PATRUNO 2, Pasquale CUOMO 3, Fabio AYALA 2, Nicola BALATO 2, Anna BALATO 4

1 Department of Medicine, Surgery and Odontology, “Scuola Medica Salernitana”, University of Salerno, Salerno, Italy; 2 Department of Clinical Medicine and Surgery, Dermatology Unit, University of Naples Federico II, Naples, Italy; 3 University of Naples “Parthenope”, Naples, Italy; 4 Department of Advanced Biomedical Sciences, Dermatology Unit, University of Naples Federico II, Naples, Italy


BACKGROUND: Contact sensitization (CS) and allergic contact dermatitis (ACD) were once thought to be rare in children. The aim of our study was to assess CS and ACD in children affected by eczematous conditions referring to our contact and occupational dermatoses service, and to compare the obtained data to the results of a similar study performed in our Department in late eighties.
METHODS: A retrospective analysis of patch test data from the Database of Contact Allergy of the Dermatology Department - University Federico II of Naples was performed. Moreover results were compared to previous data recorded and analyzed in our centre.
RESULTS: Of the 416 examined patients, tested during 2005-2010 with the paediatric series, 37.5% developed at least one positive reaction, 15.4% was diagnosed with ACD. The most common allergen was nickel sulphate (16.8%) and the most frequently involved body sites were head and neck (16.3%). Compared to the 1989 study data, our current results highlighted an increase of CS (p<0.001) and ACD diagnosis (p<0.01).
CONCLUSIONS: ACD and CS are significantly increased during the last 20 years in our young patients population. The widespread chemical use and premature adult-like attitude may be responsible for earlier and extended exposure to sensitizers.

KEY WORDS: Allergic contact dermatitis - Contact sensitization - Patch test - Children

inizio pagina

Publication History

Per citare questo articolo

Corresponding author e-mail