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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

Rivista di Dermatologia e Malattie Sessualmente Trasmesse


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2016 Nov 15

Copyright © 2016 EDIZIONI MINERVA MEDICA

lingua: Inglese

Pustular eruption associated with granulocyte colony-stimulating factor treatment

Maria B. BRUMANA 1, Irene RUSSO 1, Renato ZAMBELLO 2, Mauro ALAIBAC 1

1 Unit of Dermatology, University of Padua, Padua, Italy; 2 Unit of Hematology, University of Padua, Padua, Italy


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We report a case of localized pustular eruption on the face in a patient with Hodgkin lymphoma treated with granulocyte colony-stimulating factor for the development of chemotherapy-induced neutropenia. The administration of granulocyte colony-stimulating factor and the level of neutrophils were closely associated with disease activity, and negative cultures ruled out the hypothesis of an infective etiology. Because of the role of colony-stimulating factor in mobilization of the neutrophils we considered this phenomenon a skin reaction caused by granulocyte colony- stimulating factor-driven neutrophil accumulation.

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Brumana MB, Russo I, Zambello R, Alaibac M. Pustular eruption associated with granulocyte colony-stimulating factor treatment. G Ital Dermatol Venereol 2016 Nov 15. 

Corresponding author e-mail

mauro.alaibac@unipd.it