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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
Rivista di Dermatologia e Malattie Sessualmente Trasmesse
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 2015 Oct 01
Recurrent proliferating trichilemmal cyst of the scalp. Case report
Garetto F., Morozzo G., Morozzo U., Rosato L. ✉
Department of Surgery, Ivrea - Cuorgné Hospital, Italy
BACKGROUND: Pilar tumors, commonly called trichilemmal cysts, are usually benign in nature, malignant transformation (so called proliferating pilar tumors or proliferating trichilemmal cysts - PTCs) with high recurrence rates, local invasion and metastases have been described.
CASE OUTLINE: A 64-year-old women presented to our hospital with a recurrent ulcerated mass lesion of the scalp. Non-contrast-enhanced computed tomography scan of the head was performed. The mass was managed by complete excisional biopsy and the defect closure was achieved by using a full-thickness skin graft. Histopathological analysis revealed the characteristic structures of PTC; in addition foci of squamous pearls, squamous cells with pleomorphic nuclei suggestive of cellular atypia and increased typical mitotic activity were also noticed.
DISCUSSION: PTCs are related to high recurrency rates, local invasion and possible metastases. Radical surgical treatment and precise histological analysis are essential in order to achieve a fast and complete healing. Cooperation of the clinician and the pathologist is essential for accurate diagnosis, treatment and follow-up planning.