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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
Rivista di Dermatologia e Malattie Sessualmente Trasmesse
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 2015 Sep 16
Cardiac involvement in cutaneous sarcoidosis: case reports and review of the literature
Drago F. 1, Ciccarese G. 1, Cittadini G. 2, Drago F. 1, Rosa G. M. 3, Cozzani E. 1, Parodi A. 1 ✉
1 DISSAL, Department of Dermatology, IRCCS A.O.U. San Martino-IST, Genoa, Italy;
2 DICMI, Department of Radiology, IRCCS A.O.U. San Martino-IST, Genoa, Italy;
3 University of Genoa, IRCCS AOU San Martino - IST, Department of Internal Medicine, Genova , Italy
AIM: Sarcoidosis is a chronic multisystem disease that usually has a good prognosis but in some cases, especially when cardiac involvement occurs, the outcome is fatal. Cardiac sarcoidosis is insidious to diagnose because it is usually asymptomatic and when clinically apparent, it may have a wide variety of manifestations. The aim of this study was to investigate the possible cardiac involvement in cutaneous sarcoidosis patients.
METHODS: Diagnosis of cutaneous sarcoidosis was confirmed by skin biopsy, laboratory tests and radiological findings in 13 Caucasian Patients. To evaluate cardiac damage, Electrocardiogram, echocardiography and contrast-enhanced cardiac magnetic resonance were performed.
RESULTS: Magnetic resonance identified cardiac sarcoidosis only in one of the cutaneous sarcoidosis patients.
CONCLUSIONS: We suggest to investigate cardiac involvement in patients with cutaneous sarcoidosis, even if asymptomatic, since cardiac lesions are frequently associated with a poorer prognosis.