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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
Rivista di Dermatologia e Malattie Sessualmente Trasmesse
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
PHYSICIANS’ POINT OF VIEW ON ACTINIC KERATOSIS
Giornale Italiano di Dermatologia e Venereologia 2014 Aprile;149(2):193-8
Physicians’ concerns towards prescription adherence and treatment effectiveness in the clinical management of actinic keratosis
Peris K. 1, Neri L. 2, 3, Fargnoli M. C. 1, Pellacani G. 4 ✉
1 Department of Dermatology, University of L’Aquila, L’Aquila, Italy;
2 Department of Clinical and Community Sciences,University of Milan, Milan, Italy;
3 “Clinica del Lavoro Luigi Devoto”, Ca’ Granda IRCCS Foundation, Ospedale Maggiore Policlinico, Milan, Italy;
4 Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy
AIM: We report concerns toward prescription adherence and treatment effectiveness in the clinical management of actinic keratosis (AK) in Italy.
METHODS: We carried out a cross-sectional web-based survey among Italian dermatologists across Italy. Physicians were asked to answer a self-administered questionnaire about their concerns around AK therapy and barriers to patients’ adherence. Each physician also profiled his last patient and answered items concerning his experience with topical treatments and the suitability of current and future treatment options for the profiled patient.
RESULTS: Fifty practitioners answered the survey. Most dermatologists agreed that field-therapy is a key element for the management of AK in most patients, and 76% (N.=38) agreed that topical treatments were the best option in such cases given their ability to target subclinical lesions. However most interviewee underlined the importance of fostering patients’ adherence and minimizing side effects in order to maximize benefits from therapy.
CONCLUSION: We showed that features of current therapeutic options for field-directed therapy (namely long duration of treatment, intensity and duration of local skin reaction) raise practitioners’ concerns toward patients’ prescription adherence and real-world effectiveness.