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ULTIMO FASCICOLOGIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

Rivista di Dermatologia e Malattie Sessualmente Trasmesse

Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014

Periodicità: Bimestrale

ISSN 0392-0488

Online ISSN 1827-1820

 

Giornale Italiano di Dermatologia e Venereologia 2014 Aprile;149(2):161-6

 ORIGINAL ARTICLES

Melanoma detection in Italian pigmented lesion clinics

Argenziano G. 1, Moscarella E. 1, Annetta A. 2, Battarra V. C. 3, Brunetti B. 4, Buligan C. 5, Cantisani C. 6, Capizzi R. 7, Carbone A. 8, Carlino A. 9, Corsetti V. 10, Damiano A. 9, De Salvo V. 11, De Simone P. 8, Di Caterino P. 3, Fargnoli M. C. 12, Ferrari A. 8, Fossati B. 7, Frascione P. 13, Ghigliotti G. 14, González Inchaurraga M. A. 15, Guerriero C. 7, Landi C. 16, Mazzoni L. 17, Mirizzi S. 18, Palazzo G. 19, Pedretti A. 9, Peris K. 12, Piemonte P. 13, Rossi A. 6, Satta R. 20, Savoia F. 21, Scalvenzi M. 22, Stanganelli I. 17, Stinco G. 5, Zampieri P. 15, Zalaudek I. 23

1 Skin Cancer Unit, Arcispedale Santa Maria Nuova, IRCCS Reggio Emilia, Italy;
2 Azienda U.S.L. Latina, Italy;
3 Unit of Oncologic Dermatology and Cutaneous Neoformation Surgery, “Sant’Anna e San Sebastiano” Hospital, Caserta, Italy;
4 Unit of Dermatology, Santa Maria della Speranza Hospital, Battipaglia, Salerno, Italy;
5 Department of Clinical and Experimental Pathology and Medicine DISM, Institute of Dermatology, University of Udine, Udine, Italy;
6 Department of Dermatology, La Sapienza University of Rome, Policlinico Umberto I, Rome, Italy;
7 Diagnosis and Cutaneous Melanoma Therapy, Sacro Cuore Catholic University, Rome, Italy;
8 Department of Oncologic Dermatology, San Gallicano Dermatological Institute, Rome, Italy;
9 S. Anna Clinical Institute, Brescia, Italy;
10 Ambulatori Oncologici Raphael, Brescia, Italy;
11 Operative Unit of Dermatology, Bianchi-Melacrino-Morelli Hospital, Reggio Calabria, Italy;
12 Department of Dermatology, University of L’Aquila, L’Aquila, Italy;
13 Unit of Dermatological Health Prevention and Promotion, San Gallicano Institute, Rome, Italy;
14 Dermatologic Clinic, San Martino Hospital - IST IRCCS, Genoa, Italy;
15 Centro di Riferimento per la Dermoscopia e Videodermatoscopia, Azienda Sanitaria dell’Alto Adige, Trento, Italy, Dermatology Division, F. Tappeiner Hospital, Merano, Bolzano, Italy;
16 Dermatologic Unit, Surgical Department, “Infermi” Hospital, Rimini, Italy;
17 Skin Cancer Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, IRCCS IRST, Meldola, Forlì-Cesena, Italy;
18 Studio Mirizzi, Parma, Italy;
19 Operative Unit of Dermatology, Tinchi Hospital, Pisticci, Matera, Italy;
20 Department of Surgical, Microsurgical, Medical Sciences, Sassari University, Sassari, Italy;
21 Unit of Dermatology, AUSL Ravenna, Lugo, Ravenna, Italy;
22 Department of Clinical Medicine and Surgery, Dermatology, University of Naples Federico II, Napoli, Italy;
23 Department of Dermatology, Medical University of Graz, Graz, Austria

AIM: Accuracy in melanoma detection is important to recognize early curable melanomas and to minimize the unnecessary excision of benign lesions. The aim of this paper was to evaluate melanoma screening accuracy of Italian pigmented lesion clinics in terms of number needed to excise (NNE), melanoma thickness, and number of melanomas diagnosed during patient follow-up.
METHODS: Information on all skin tumors excised in 2011 were extracted from the databases of the participating centers. Information whether the lesion was excised at the baseline examination or during patient follow-up was recorded, as well as the overall number of patients examined in each center in 2011.
RESULTS: After e-mail solicitation, 22 of 40 centers agreed to participate. A total of 8229 excised lesions were collected. The overall number of examined patients was 86.564, thus 9.5% of screened patients had a lesion removed. Of the excised lesions, 866 were diagnosed as melanoma (1% of examined patients) and 5311 (88.9%) were melanocytic nevi. Three NNE were calculated giving values of 7.9 excised lesions to find 1 melanoma, 7.1 melanocytic lesions to find 1 melanoma, and 3.7 lesions to find 1 skin malignancy. The median melanoma thickness was 0.6 mm, with only 15.1% of melanomas ≥1 mm of thickness. Melanomas detected over time were 96 (11.1%; mean thickness, 0.3 mm), with 15.6% of lesions excised after short-term follow-up and 84.4% after long-term follow-up.
CONCLUSION: The NNE values comparable to those achieved in specialized clinical settings and the high number of early melanomas diagnosed at the baseline examination or during patient follow-up indicate a high level of accuracy in melanoma screening achieved by Italian pigmented lesion clinics.

lingua: Inglese


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