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THE JOURNAL OF CARDIOVASCULAR SURGERY
Rivista di Chirurgia Cardiaca, Vascolare e Toracica
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632
The Journal of Cardiovascular Surgery 2016 Apr 21
Early evaluation of precise deployment with the new low profile Zenith Alpha Thoracic Endoprosthesis in thoracic aortic disease
Bianca PANE, Giovanni SPINELLA, Maria C. PERFUMO, Debora MUSIO, Simone MAMBRINI, Cesare FERRERO, Valerio GAZZOLA, Domenico PALOMBO ✉
Vascular and Endovascular Surgery Unit, University Hospital IRCCS San Martino-IST, University of Genoa, Italy
BACKGROUND: Endovascular treatment of thoracic aortic disease currently allows to treat high risk patients with better results than open repair. It represents the first option for treatment according to the most recent guidelines. The aim of the study is to evaluate the early results of the low profile Zenith Alpha Thoracic Endoprosthesis (ZATE).
METHODS: Between October 2012 and July 2015, 14 asymptomatic patients were treated with ZATE. 10 patients were male, mean age was 71, 7 years (range 58 – 85 years). 8 patients presented with atherosclerotic aortic aneurysm (7 thoracic aneurysm and 1 type I thoracoabdominal aneurysm), 2 chronic type B aortic dissection, 1 type IV endoleak 5 years after TEVAR, 3 aortic arch penetrating ulcer complicated by pseudoaneurysm. Hybrid staged procedures in 11 patients included 7 total aortic arch debranching (1 single (innominate) chimney stent graft + Carotid-Carotid-Subclavian), 2 carotid-carotid-subclavian artery bypass, 2 carotid- subclavian artery bypass.
RESULTS: No 30-day mortality or major complications were observed. The mean length of stay was 7.3 days (range 4-14 days). Mean procedure time, X ray time and Contrast load were 115 min (range 90-150 min), 20 min (range 10-30) and 79 mL (range 40-120 mL) respectively. 25 stent grafts were implanted. The mean follow up was 21 months (range 14 - 32 months). No mortality and no major complications were observed during the follow-up. In case of arch debranching with landing 0 and 1 zone the mean distance between the beginning of the endoprosthesis and the debranching inflow vessel was 5.5 mm (±2.4 mm)
CONCLUSIONS: The use of ZATE could be a viable alternative for treating patients with aortic arch proximal landing zone to facilitate the precise deployment. Larger case studies and longer follow-up are needed.