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THE JOURNAL OF CARDIOVASCULAR SURGERY

Rivista di Chirurgia Cardiaca, Vascolare e Toracica


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REVIEWS  DRUG-ELUTING TECHNOLOGIES: WHERE ARE WE


The Journal of Cardiovascular Surgery 2011 Aprile;52(2):225-9

lingua: Inglese

Drug-eluting stents above the knee

Minar E.

Department of Angiology, Medical University Vienna, Vienna, Austria


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There are only very few trials concerning use of drug-eluting stents (DES) in the femoropopliteal segment. While earlier trials using a sirolimus-eluting polymer-coated stent and an everolimus-eluting stent failed to demonstrate improved mid-term patency compared with a bare-metal stent, the recently presented ‑ however still unpublished – data with the Zilver PTX stent using a polymer-free paclitaxel coating are very promising. Before we can make definite conclusions and recommendations, we have to see longer-term follow-up data. A potential future improvement of local drug application for the necessary time span without the disadvantages of permanent stent implantation can be expected by the development of completely bioabsorbable DES.

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erich.minar@meduniwien.ac.at