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THE JOURNAL OF CARDIOVASCULAR SURGERY

Rivista di Chirurgia Cardiaca, Vascolare e Toracica


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REVIEW  AN UPDATE ON AVAILABLE STENTS FOR THE MANAGEMENT OF ABDOMINAL AORTIC ANEURYSMS


The Journal of Cardiovascular Surgery 2009 Aprile;50(2):153-8

lingua: Inglese

Endurant stent-graft system: preliminary report on an innovative treatment for challenging abdominal aortic aneurysm

Verhagen H. J. M., Torsello G., De Vries J-P. P. M., Cuypers P. H., Van Herwaarden J. A., Florek H-J., Scheinert D., Eckstein H-H., Moll F. L.

1 Department of Vascular Surgery Erasmus Medical Center, Rotterdam, The Netherlands
2 Department of Vascular Surgery St. Franziskus-Hospital, Münster, Germany
3 Department of Vascular Surgery St. Antonius Hospital, Nieuwegein, The Netherlands 4 Department of Vascular Surgery Catharina Hospital, Eindhoven, The Netherlands
5 Department of Vascular Surgery Universitair Medisch Centrum Utrecht Utrecht, The Netherlands
6 Department of Vascular Surgery Krankenhaus Dresden-Friedrichstadt Städtisches Krankenhaus, Dresden, Germany
7 Park-Krankenhaus Leipzig-Südost GmbH Klinik für Innere Medizin I/AngiologieKardiologie, Leipzig, Germany
8 Department of Vascular Surgery/Vascular Center Medical Center “München rechts der Isar” (MRI) Technical University Munich, München, Germany


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The evolution of stent-grafts and endovascular delivery systems has substantially improved the application rate for and patient outcomes with endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA), but further development is needed in order to reduce the continuing incidence of complications and secondary re-interventions. Severe angulations at the proximal aneurysm neck and tortuous, calcified, and small iliac arteries are still recognized as important risk factors for successful EVAR of AAA and hence as criteria for exclusion of many potential patients. The Endurant stent-graft is part of a next-generation system that was designed with the clear intention of expanding the applicability of EVAR for AAA while also continuing to improve treatment outcomes and reduce complications. Innovative features of the system design include anchoring pins for ensuring proximal fixation, wire-formed M-shape body stents for improved flexibility and conformability, and a low-profile delivery system with hydrophilic coating that improves trackability and pushability to facilitate the vascular access even in small challenging arteries. Initial clinical experience with the Endurant stent-graft system, including preliminary results from the first-in-human European trial of the device, has demonstrated that the device can be delivered and deployed safely, even in highly angulated anatomies. Technical success was achieved in 90.3% of the patients in the trial. No device-related serious adverse events were seen during the first follow-up period, and no device-related deaths were reported. This new stent-graft will potentially enlarge the patient population suitable for EVAR of AAA.

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