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THE JOURNAL OF CARDIOVASCULAR SURGERY
Rivista di Chirurgia Cardiaca, Vascolare e Toracica
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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CASE REPORTS THORACIC SECTION
The Journal of Cardiovascular Surgery 2001 June;42(3):425-7
Pericardial mesothelioma following mantle field radiotherapy
Velissaris T. J., Tang A. T. M., Millward-Sadler G. H. *, Morgan J. M. **, Tsang G. M.
From the Departments of Cardiothoracic Surgery *Pathology and **Cardiology Southampton General Hospital Southampton, United Kingdom
A 49-year-old female was referred with recurrent pericardial effusion following mantle field radiotherapy for Hodgkin’s lymphoma. She underwent video-assisted thoracoscopy and resection of a pericardial window. Intraoperatively she suffered a cardiac arrest and subsequently died in the early postoperative period despite maximal therapy. Pathological examination revealed extensive myocardial fibrosis and multiple nodules of pericardial mesothelioma. The latter has hitherto not been recognised following mediastinal radiation. The cardiac complications of mantle field radiotherapy are discussed.