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THE JOURNAL OF CARDIOVASCULAR SURGERY

Rivista di Chirurgia Cardiaca, Vascolare e Toracica


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The Journal of Cardiovascular Surgery 2001 June;42(3):425-7

Copyright © 2009 EDIZIONI MINERVA MEDICA

lingua: Inglese

Pericardial mesothelioma following mantle field radiotherapy

Velissaris T. J., Tang A. T. M., Millward-Sadler G. H. *, Morgan J. M. **, Tsang G. M.

From the Departments of Cardiothoracic Surgery *Pathology and **Cardiology Southampton General Hospital Southampton, United Kingdom


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A 49-­year-old ­female was ­referred ­with recur­rent per­i­car­dial effu­sion fol­lowing ­mantle ­field radio­therapy for ­Hodgkin’s lym­phoma. She under­went ­video-­assisted tho­ra­cos­copy and resec­tion of a per­i­car­dial ­window. Intra­op­er­a­tively she suf­fered a car­diac ­arrest and sub­se­quently ­died in the ­early post­op­er­a­tive ­period ­despite max­imal ­therapy. Path­o­log­ical exam­ina­tion ­revealed exten­sive myo­car­dial ­fibrosis and mul­tiple nod­ules of per­i­car­dial mesoth­e­lioma. The ­latter has ­hitherto not ­been rec­og­nised fol­lowing med­i­as­tinal radi­a­tion. The car­diac com­pli­ca­tions of ­mantle ­field radio­therapy are dis­cussed.

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