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THE JOURNAL OF CARDIOVASCULAR SURGERY

Rivista di Chirurgia Cardiaca, Vascolare e Toracica


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The Journal of Cardiovascular Surgery 2001 Febbraio;42(1):53-6

lingua: Inglese

Primary cardiac leiomyosarcoma originating from the pulmonary valve. Case report and review of the literature

Schröder S., Walker T. *, Greschniok A. **, Herdeg C., Karsch K. R., Ziemer G. *

From the Department of Internal Medicine Division of Cardiology
*Department of Surgery Division of Cardiothoracic Surgery
**Department of Pathology University of Tübingen, Tübingen, Germany


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Primary car­diac ­tumours are ­rare find­ings (inci­dence 0.02% accord­ing to a ­recent met­a­-anal­y­sis) ­with dis­mal prog­no­sis. Approximately 25% are malig­nant, most­ly rep­re­sent­ed by sar­co­mas. Among ­these, leiom­yo­sar­co­mas are excep­tion­al. Treatment for pri­mary car­diac leiom­yo­sar­co­mas con­sists of rad­i­cal sur­gi­cal resec­tion fol­lowed by adju­vant radi­a­tion ther­a­py and/or chem­o­ther­a­py. The ­mean sur­vi­val ­after sur­gery and adju­vant ther­a­pies is 6.8 ­months. We ­present a ­rare ­case of a 40- ­year-old ­male ­patient ­with a pri­mary car­diac leio­my­sar­co­ma orig­i­nat­ing ­from the pul­mo­nary ­valve. This ­patient ­died ­after sur­gery and implan­ta­tion of a homo­graft of the pul­mo­nary ­trunk. Furthermore, the lit­er­a­ture has ­been ­reviewed.

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