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THE JOURNAL OF CARDIOVASCULAR SURGERY

Rivista di Chirurgia Cardiaca, Vascolare e Toracica


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The Journal of Cardiovascular Surgery 1999 October;40(5):741-8

Copyright © 2000 EDIZIONI MINERVA MEDICA

lingua: Inglese

FDG/PET and spiral CT image fusion for medistinal lymph node assessment of non-small cell lung cancer patients

Magnani P., Carretta A.*, Rizzo G., Fazio F., Vanzulli A.**, Lucignani G., Zannini P.*, Messa C., Lanconi C., Gilardi M. C., Del Maschio A.**

From the Department of Nuclear Medicine *Department of Thoracic Surgery **Department of Diagnostic Radiology INB-CNR, Institute H. S. Raffaele University of Milan, Milan, Italy


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Background. To ­assess the poten­tial use­ful­ness of
18F-FDG/PET and spi­ral-CT imag­es con­cur­rent assess­ment and coreg­is­tra­tion in stag­ing med­i­as­ti­nal ­lymph ­node involve­ment in ­patients ­with non ­small ­cell ­lung can­cer.
Methods. 28 ­patients wait­ing to under­go sur­gi­cal treat­ment under­went spi­ral-CT and PET exam­ina­tions on the ­same day. The ­results of the two stud­ies ­were inter­pret­ed sep­ar­ate­ly, togeth­er (CT&PET) and fol­low­ing ­their ­fusion in a sin­gle ­image (CT+PET). Results of spi­ral-CT, PET, CT&PET and CT+PET ­were ­assessed ­with ­respect to the his­to­log­i­cal diag­no­sis.
Results. A cor­rect assess­ment of med­i­as­ti­nal ­lymph ­nodes was ­achieved by spi­ral-CT in 21 of the 28 ­patients, in 22 of the 28 ­patients by PET, in 24 ­patients by CT&PET and in 25 ­patients by CT+PET.
Conclusions. CT+PET is ­more accu­rate ­than spi­ral-CT and PET ­alone in stag­ing med­i­as­ti­nal ­lymph ­node involve­ment in ­lung can­cer ­patients, ­with pos­sible impli­ca­tions for ­their prog­no­sis and ther­a­py

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