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Rivista di Chirurgia Cardiaca, Vascolare e Toracica

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The Journal of Cardiovascular Surgery 1999 Agosto;40(4):603-5

lingua: Inglese

Vocal ­fold injection of col­la­gen for uni­lat­er­al ­vocal ­fold par­al­y­sis ­caused by ­chest dis­eas­es

Sagawa M., Sato M., Fuji­mu­ra S., Sak­u­ra­da A., Tak­a­ha­shi H., Kon­do T., Endo C., Tani­ta T., Ono S., Sai­to Y.

From the Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan


Background. Patients hav­ing malig­nant ­chest dis­eas­es some­times suf­fer ­from ­vocal ­fold par­al­y­sis. Treatment for ­vocal ­fold par­al­y­sis is impor­tant for ­such ­patients, ­because ­vocal ­fold par­al­y­sis caus­es ­lack of the ver­sa­til­ity of the ­human ­voice ­which is essen­tial for our com­mu­ni­ca­tion.
Methods. Seventeen ­patients suf­fer­ing ­from uni­lat­er­al ­vocal ­fold par­al­y­sis ­were treat­ed ­with ­vocal ­fold injec­tions of col­la­gen. Three ­patients ­received ­twice, and 20 treat­ments ­were con­duct­ed. A flex­ible bron­chof­i­ber­scope was ­used ­under ­local anes­the­sia in ­order to ­observe the ­whole pro­ce­dure of ­vocal ­fold injec­tion. Using an injec­tor and a ­long nee­dle, col­la­gen was inject­ed ­with trans­cu­ta­ne­ous tech­nique main­ly ­through the cri­coth­yr­oid mem­brane. The ­amount of col­la­gen was deter­mined ­with bron­chos­cop­ic find­ings.
Results. During and ­after treat­ment, no com­pli­ca­tion was ­observed. Of 20 treat­ments, a ­marked improve­ment was ­observed in 8, and mod­er­ate improve­ment was ­observed in 9 treat­ments.
Conclusions. Vocal ­fold injec­tion of col­la­gen is a ­very use­ful and ­safe treat­ment for uni­lat­er­al ­vocal ­fold par­al­y­sis ­caused by ­chest dis­eas­es.

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