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THE JOURNAL OF CARDIOVASCULAR SURGERY

Rivista di Chirurgia Cardiaca, Vascolare e Toracica


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The Journal of Cardiovascular Surgery 1999 August;40(4):603-5

Copyright © 2000 EDIZIONI MINERVA MEDICA

lingua: Inglese

Vocal fold injection of collagen for unilateral vocal fold paralysis caused by chest diseases

Sagawa M., Sato M., Fujimura S., Sakurada A., Takahashi H., Kondo T., Endo C., Tanita T., Ono S., Saito Y.

From the Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan


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Background. Patients hav­ing malig­nant ­chest dis­eas­es some­times suf­fer ­from ­vocal ­fold par­al­y­sis. Treatment for ­vocal ­fold par­al­y­sis is impor­tant for ­such ­patients, ­because ­vocal ­fold par­al­y­sis caus­es ­lack of the ver­sa­til­ity of the ­human ­voice ­which is essen­tial for our com­mu­ni­ca­tion.
Methods. Seventeen ­patients suf­fer­ing ­from uni­lat­er­al ­vocal ­fold par­al­y­sis ­were treat­ed ­with ­vocal ­fold injec­tions of col­la­gen. Three ­patients ­received ­twice, and 20 treat­ments ­were con­duct­ed. A flex­ible bron­chof­i­ber­scope was ­used ­under ­local anes­the­sia in ­order to ­observe the ­whole pro­ce­dure of ­vocal ­fold injec­tion. Using an injec­tor and a ­long nee­dle, col­la­gen was inject­ed ­with trans­cu­ta­ne­ous tech­nique main­ly ­through the cri­coth­yr­oid mem­brane. The ­amount of col­la­gen was deter­mined ­with bron­chos­cop­ic find­ings.
Results. During and ­after treat­ment, no com­pli­ca­tion was ­observed. Of 20 treat­ments, a ­marked improve­ment was ­observed in 8, and mod­er­ate improve­ment was ­observed in 9 treat­ments.
Conclusions. Vocal ­fold injec­tion of col­la­gen is a ­very use­ful and ­safe treat­ment for uni­lat­er­al ­vocal ­fold par­al­y­sis ­caused by ­chest dis­eas­es.

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