Home > Riviste > The Journal of Cardiovascular Surgery > Fascicoli precedenti > The Journal of Cardiovascular Surgery 1998 October;39(5) > The Journal of Cardiovascular Surgery 1998 October;39(5):599-607

ULTIMO FASCICOLO
 

ARTICLE TOOLS

Estratti

THE JOURNAL OF CARDIOVASCULAR SURGERY

Rivista di Chirurgia Cardiaca, Vascolare e Toracica


Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,632


eTOC

 

ORIGINAL ARTICLES  CARDIAC PAPERS


The Journal of Cardiovascular Surgery 1998 October;39(5):599-607

Copyright © 2000 EDIZIONI MINERVA MEDICA

lingua: Inglese

Tepid system­ic per­fu­sion and inter­mit­tent iso­ther­mic ­blood car­di­o­ple­gia in cor­o­nary sur­gery

Lucia­ni N., Mar­ti­nel­li L., Gau­di­no M., Ales­san­dri­ni F., Glie­ca F., Pos­sa­ti G.

From ­the Department of Cardiac Surgery and of Anaesthesiology Catholic University, Rome, Italy


PDF  


Background. To eval­u­ate ­the safe­ty ­and effec­tive­ness of tep­id per­fu­sion ­and iso­ther­mic ­blood car­di­o­ple­gia in cor­o­nary sur­gery.
Methods. We stud­ied 200 ­patients under­go­ing myo­car­dial revas­cu­lar­iza­tion: 100 pro­ce­dures ­were per­formed ­with mod­er­ate system­ic hypo­ther­mia (28°C) ­and ­cold crys­tal­loid car­di­o­ple­gia (4°C); ­the oth­er 100 ­patients ­received tep­id system­ic per­fu­sion (TP) (34°C) ­and inter­mit­tent ­blood car­di­o­ple­gia at ­the ­same tem­per­a­ture accord­ing to ­the min­i­car­di­o­ple­gia tech­nique (Group 2). The ­two ­groups ­were com­par­able with ­regards to ­age, ­extent of dis­ease, pre­op­er­a­tive ­left ven­tric­u­lar func­tion ­and ­extra-cor­po­real cir­cu­la­tion (­ECC) ­time.
Results. In ­the tep­id ­group we ­observed a high­er inci­dence of spon­ta­ne­ous resump­tion of car­diac ­rhythm at ­cross-­clamp remov­al com­pared to ­the hypo­ther­mic ­group (93% vs 34%; p<0.001). No dif­fer­ence ­was ­found in car­diac ­index at spec­i­fied inter­vals, myo­car­dial ­enzymes, ­inotrope require­ments, arrhyth­mi­as, ­need ­for vas­o­pres­sors ­and ­postoper­a­tive ­blood ­loss. Fluid bal­ance at ­the ­end of ­ECC ­was sig­nif­i­cant­ly low­er in ­the tep­id ­group (343±635 ml vs 883±925 ml; p<0.001). Hospital mor­tal­ity ­and mor­bid­ity ­were ­the ­same in ­the ­two ­groups.
Conclusions. Our ­data sug­gest ­that TP ­and iso­ther­mic ­blood car­di­o­ple­gia rep­re­sent a sim­ple, ­safe ­and effec­tive meth­od of system­ic ­and myo­car­dial pro­tec­tion ­which ­may be an alter­na­tive to tra­di­tion­al hypo­ther­mia.

inizio pagina

Publication History

Per citare questo articolo

Corresponding author e-mail