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CURRENT ISSUEITALIAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

A Journal on Vascular and Endovascular Surgery


Official Journal of the Italian Society of Vascular and Endovascular Surgery
Indexed/Abstracted in: EMBASE, Scopus


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Italian Journal of Vascular and Endovascular Surgery 2015 December;22(4):237-48

language: English

The roles of drug-eluting technology and atherectomy in infrapopliteal occlusive disease

Yiu W. K., Conte M. S.

Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA, USA


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Chronic limb threatening ischemia (CLI) is often associated with occlusive disease of the infrapopliteal arteries. Percutaneous balloon angioplasty has been a standard treatment modality for infrainguinal arterial occlusive disease, but its use is limited by its relatively high restenosis rate and the frequent need of re-intervention, especially in below-the-knee (BTK) arteries. In the past decade, ongoing technology innovations, such as drug-coated balloon and drug-eluting stents have shown promising results in peripheral arterial disease. Atherectomy, a plaque debulking technology capable of disobliterating heavily calcified vessels, has also been advocated for BTK disease. However there is little in the way of high-quality comparative data to discern the relative efficacy of these interventional approaches versus each other, or versus open surgery. This review provides a current summary of evidence for these technologies in the setting of CLI and BTK occlusive disease.

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