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A Journal on Vascular and Endovascular Surgery
Giornale Italiano di Chirurgia Vascolare 2003 March;10(1):15-25
language: English, Italian
Endovascular treatment of critical limb ischemia in diabetic patients
Porcellini M., Del Guercio L., Cecere D., Spinetti F., Di Lella D., Bracale G.
Cattedra di Chirurgia Vascolare Università degli Studi di Napoli Federico II, Napoli
Background. The influence of diabetes on limb salvage is a controversial question. The aim of this study was to evaluate the outcomes of diabetic patients and non-diabetic patients with critical limb ischemia undergoing arterial endovascular procedures.
Methods. The records of 33 consecutive patients who had undergone endovascular treatment for limb-threatening ischemia over the past 7 years, including diabetic patients (Group I; n=16) and non-diabetic patients (Group II; n=17), were reviewed.
Results. No significant differences were found between Group I and II patients with respect to age, gender, risk factors, surgical indications, preoperative ankle-brachial indices. The limb salvage rates for Group I and II patients 30 days after treatment were 77.8% and 94.4% (p = n.s.), respectively. Of 4 early amputations in the diabetic group, 3 were performed in limbs with patent revascularisation. There was no procedure-related death (<30 days). After a median follow-up of 25 months (range 9-84 months) in diabetic patients and 30 months (range 7-72 months) in non-diabetic patients, the limb survival rates were 66.7% and 83.3% (p = not significant). Three (18.7%) late deaths occurred in Group I and 1 (5.9%) in Group II patients (p = not significant) from cardiac disease or cancer.
Conclusions. The results of arterial endovascular therapy in diabetic patients showed limb-salvage rates similar to those found in non-diabetic patients.