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The Journal of Sports Medicine and Physical Fitness 2013 April;53(2):198-202

language: English

Relationship between inflammatory markers of cardiovascular disease and VO2peak in asymptomatic females

Omran Simin F 1, Narges Z. 2, Sajad A. 3, Parisa Y. 4, Omrani Vahid F. 5

1 Department of Exercise Physiology, Tehran University, Tehran, Iran;
2 Sama Technical and Vocational Training School, Islamic Azad Branch, Tehran, Iran;
3 Department of Exercise Physiology, Shahid Beheshti University, Tehran, Iran;
4 Department of Biomedical Engineering, Duke University, Durham, NC, USA;
5 College of Veterinary Medicine, Ferdowsi University, Mashhad, Iran


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Aim: The objective of this study was to investigate the relationship between inflammatory markers of cardiovascular disease (IL-6 and acute-phase reactants) and VO2peak in asymptomatic females.
Methods: Study subjects were females not affected by coronary heart diseases. Forty healthy female subjects (age, 45±4.2 years; height, 161±3.5 cm; weight, 65±3.1 kg; history of regular physical activity, 5.2±0.45 years) participated in this study
Results: Analysis of data was carried out by Pearson’s correlation. Statistical analysis of data indicated a negative significant relationship between IL-6 and VO2peak (r=-0.48, r2=0.23, P<0.048), CRP and VO2peak (r=-0.40, r2= 0.16, P<0.002), fibrinogen and VO2peak (r=-0.42, r2=0.17, P<0.001), and WBC and VO2peak (r=-0.22, r2=0.04, P<0.044).
Conclusion: In conclusion higher circulating levels of IL-6, CRP and fibrinogen are associated with lower VO2peak in females.

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siminomran@ut.ac.ir