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THE JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS
A Journal on Applied Physiology, Biomechanics, Preventive Medicine,
Sports Medicine and Traumatology, Sports Psychology
Indexed/Abstracted in: Chemical Abstracts, CINAHL, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,111
Original articles BODY COMPOSITION, SPORT NUTRITION AND SUPPLEMENTATION (ergogenics)
The Journal of Sports Medicine and Physical Fitness 2006 September;46(3):458-61
Effects of vitamin E supplementation on oxidative stress at rest and after exercise to exhaustion in athletic students
Gaeini A. A. 1, Rahnama N. 2, 3, Hamedinia M. R. 4
1 Faculty of Physical Education University of Tehran, Tehran, Iran
2 Research Institute for Sport and Exercise Sciences Liverpool John Moores University, Liverpool, UK
3 Department of Physical Education and Sport Science Isfahan University, Isfahan, Iran
4 Faculty of Physical Education Sabzevar Teacher Training University, Sabzevar, Iran
Aim. The purpose of this study is to determine the effect following exercise to exhaustion of vitamin E supplementation on oxidative stress in athletic students.
Methods. Twenty male students voluntarily participated in the study and were randomly assigned (double blind) to either a vitamin E (daily dose of 450 mg of α-tocopherol for a period of 8 weeks) or a placebo group (took capsules containing 450 mg of lactose for 8 weeks). Before and after 8 weeks blood samples were collected at rest and after exercise to exhaustion. Oxidative stress markers were malondialdehyde (MDA), carbonylated proteins (CP) and creatine kinase (CK). Also, the effect of vitamin E on ergometer cycling time, as an example of endurance performance, was evaluated.
Results. ANOVA and independent t-tests indicated that vitamin E supplementation did not significantly change (P>0.05) MDA, CP and CK values at rest, after exercise to exhaustion, and cycling time, but plasma volume after exercise to exhaustion significantly decreased (P<0.05).
Conclusions. Although vitamin E supplementation had no effect on exercise performance or capacity in athletic students, further investigation is required using larger numbers of subjects and measures of vitamin E before unequivocal conclusion can be stated.