Advanced Search

Home > Journals > Panminerva Medica > Past Issues > Articles online first > Panminerva Medica 2016 Jun 16



A Journal on Internal Medicine

Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,6

Frequency: Quarterly

ISSN 0031-0808

Online ISSN 1827-1898


Panminerva Medica 2016 Jun 16

Effect of magnesium, probiotic, and vitamin food supplementation in healthy subjects with psychological stress and evaluation of a persistent effect after discontinuing intake

Francois A. ALLAERT 1, Stefanie COURAU 2, Anne FORESTIER 2

1 Health Claim Evaluation Chair ESC & CenNutriment, Dijon, France; 2 Merck Laboratory, Dijon, France

BACKGROUND: To describe the changes in subjects’ psychological stress intensity under the effect of dietary supplements of magnesium, probiotics, and vitamins after one month of intake.
METHODS: Observational cohort study of subject complaining of psychological stress defined by a Perceived Stress Scale (PSS 10) score of more than 21.
RESULTS: The study covered 242 healthy volunteers, 38.6 ± 13.6 years old, among whom 79.8% were women. Under the effect of the supplementation of magnesium, probiotics, and vitamins, the psychological stress of the subjects decreased significantly from 34.1 ± 4.5 to 26.2 ± 6.1 (p<0.0001), which corresponds to an average reduction of 22.7 ± 16.0%. Fatigue decreased even more significantly from 16.8 ± 6.4 to 8.7 ± 6.2 (p<0.0001), which corresponds to an average reduction of 45.0% ± 38.1%. Analysis showed that the psychological stress level was strictly similar one month after the treatment was discontinued and therefore clearly demonstrated that the psychological benefit was maintained over time.
CONCLUSIONS: Stress and fatigue are significantly reduced by the intake of a food supplement with probiotics, magnesium, vitamins, and minerals and this effect is fully maintained one month after discontinuing the food supplement intake.

language: English


top of page