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Home > Journals > Panminerva Medica > Past Issues > Panminerva Medica 2007 September;49(3) > Panminerva Medica 2007 September;49(3):139-49



A Journal on Internal Medicine

Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,6

Frequency: Quarterly

ISSN 0031-0808

Online ISSN 1827-1898


Panminerva Medica 2007 September;49(3):139-49


Diagnosis and treatment of depression in Alzheimer’s disease: impact on mood and cognition

Appleby B. S., Roy P., Valenti A., Lee H. B.

Department of Psychiatry and Behavioral Sciences Johns Hopkins University, School of Medicine Baltimore, MD, USA

Depression, a common neuropsychiatric syndrome associated with lower quality of life (QOL), higher mortality, and higher caregiver burden, is estimated to occur in 20-50% of Alzheimer’s disease (AD) patients. Recent research suggests that depression in AD (dAD) may differ from major depression phenomenologically and etiologically. Treatment options for dAD include behavioral modifications, pharmacotherapy, and electroconvulsive therapy. Successful treatment of dAD has been reported to improve patients’ mood and QOL, as well as lower caregiver burden. Further research is needed in therapeutics of dAD to enhance treatment options and effectiveness.

language: English


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